The HAT1 Antibody from MyBioSource.com is a Rabbit Polyclonal antibody to HAT1, and Histone acetyltransferase 1. This antibody recognizes Human, and Rat antigen. The HAT1 Antibody has been validated for the following applications: ELISA, Immunofluorescence, and Western Blot.
Description
Acetylates soluble but not nucleosomal histone H4 at 'Lys-5' (H4K5ac) and 'Lys-12' (H4K12ac) and, to a lesser extent, acetylates histone H2A at 'Lys-5' (H2AK5ac). Has intrinsic substrate specificity that modifies lysine in recognition sequence GXGKXG. May be involved in nucleosome assembly during DNA replication and repair as part of the histone H3.1 and H3.3 complexes. May play a role in DNA repair in response to free radical damage